A cancer patient has made a full recovery after being injected with
billions of his own immune cells in the first case of its kind, doctors
have disclosed.
The 52-year-old, who was suffering from advanced skin cancer, was
free from tumours within eight weeks of undergoing the procedure.
After two years he is still free from the disease which had spread to his lymph nodes and one of his lungs.
Doctors took cells from the man’s own defence system that were found
to attack the cancer cells best, cloned them and injected back into his
body, in a process known as “immunotherapy”.
Experts said that the case could mark a landmark in the treatment of cancer.
It raises hopes of a possible new way of fighting the disease, which claims 150,000 lives in Britain every year.
Ed Yong, health information manager at Cancer Research UK, said:
“It’s very exciting to see a cancer patient being successfully treated
using immune cells cloned from his own body. While it’s always good news
when anyone with cancer gets the all clear, this treatment will need to
be tested in large clinical trials to work out how widely it could be
used.”
However, the treatment could prove extremely expensive and scientists
say that more research is needed to prove its effectiveness.
A dramatic example of immunotherapy was reported two years ago by one
pioneer of the field, Dr Steven Rosenberg of the US National Cancer
Institute, who eradicated cancer from two dying men using genetically
modified versions of their own cells.
Both Mark Origer and “Thomas M” were suffering from advanced melanoma
but the hope is that such methods could be customised to attack other
common cancers, notably breast, colon and lung.
Dr Rosenberg told The Daily Telegraph the new work is an “interesting
study that helps to confirm the effectiveness of cell transfer
immunotherapy for treating cancer patients. We have now treated 93
patients with metastatic melanoma using their own anti-tumour cells with
response rates up to 72 per cent. Mark Origer remains disease free now
over three years after treatment.”
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