Despite its life-saving qualities, chemotherapy has long had
a nasty reputation, known as a necessary poison for people suffering
from cancer. But in some cases, chemotherapy is so damaging that it may
even backfire and make the cancer worse, a new study has found. The
study, published in Nature Medicine, found that chemotherapy causes
damage to healthy cells, which triggers them secrete a protein that
actually sustains tumor growth, Cancer UK reported.
The researchers made the finding while trying to figure out a
major mystery: why are cancer cells are so easy to kill in a lab, but
so difficult to kill in the human body? The findings were "completely
unexpected," researchers told AFP.
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In cancer treatment, tumors often respond well at first, only to rapidly regrow and become resistant to chemotherapy later on, AFP reported. "Our
results indicate that damage responses in benign cells ... may directly
contribute to enhanced tumor growth kinetics," the research team wrote.
A solution to this problem would be chemotherapy that is better at
targeting cancer cells and avoiding healthy cells.
Previous research has found that chemotherapy can also cause brain damage. Radiation cancer treatments have also been shown to cause cancer later on.
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