At the age of 17 I was paying attention in college, but still
enjoying the student life as much as studying towards my career goals.
What I wasn’t doing was working at the cutting edge of cancer treatment
and developing a potential cure.
Angela Zhang is, and she’s just been awarded the $100,000 Grand Prize
in the Individual category of the Siemens Competition in Math, Science
& Technology. Her project was entitled “Design of Image-guided,
Photo-thermal Controlled Drug Releasing Multifunctional Nanosystem for
the Treatment of Cancer Stem Cells.”
Her creation is being heralded as a “Swiss army knife of cancer
treatment.” Zhang managed to develop a nanoparticle that can be
delivered to the site of a tumor through the drug salinomycin. Once
there it kills the cancer stem cells. However, Zhang went further and
included both gold and iron-oxide components, which allow for
non-invasive imaging of the site through MRI and Photoacoustics.
As to why she chose this as her project, Zhang explains that she was
surprised when looking at the survival rates of patients receiving
cancer treatment. As cancer stem cells are resistant to many forms of
cancer treatment, it seemed like an area worth focusing on. Her
nanoparticle is award-winning due to the fact it has the potential to
overcome cancer resistance while offering up the ability to monitor the
effects of the treatment in real-time using existing imaging techniques.
Zhang’s achievement is impressive considering she is only 17 years
old, but also due to the level of understanding required to create such a
nanoparticle in the first place. She has spent over 1,000 hours since
2009 researching and developing the particle, and wants to go on to
study chemical engineering, biomedical engineering, or physics. Her
dream job is to be a research professor.
The Siemens Competition
is in its 13th year and aims to highlight talent at the high school
level for those interested in science research. Last year 15-year-old
Benjamin Clark won the Individual category for his work into how stars
are born. In 2009 Ruoyi Jiang won for his research into chemotherapy
drug resistance.
I think we can all agree this is a very worthwhile competition, and
long may it continue if it pushes young minds to create solutions to
some of our biggest problems.
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